Peritoneal mesothelioma is a form of asbestos cancer that affects the lining of the abdominal cavity, also known as the peritoneum. Less common than pleural mesothelioma, peritoneal mesothelioma makes up less than 30% of all mesothelioma cases. Peritoneal mesothelioma seems to have a shorter latency period than pleural mesothelioma, typically presenting symptoms 20 to 30 years after exposure to asbestos.
The peritoneum is comprised of two parts--the parietal and visceral peritoneum. The visceral layer covers the internal organs and intestinal tract, while the parietal peritoneum protects the abdominal cavity. Cells in the peritoneum release a fluid that helps organ move more easily. For instance, this secretion helps the intestines move food throughout the body. When mesothelioma cancer forms in the peritoneum, the cells may overproduce this liquid, creating an excess fluid build-up.
While scientists are still unsure how asbestos causes peritoneal mesothelioma, they have a few theories. One speculation suggests that asbestos fibers are ingested through food or drink. When in the intestinal tracts, these fibers may migrate to the peritoneum. On the other hand, others believe asbestos fibers are inhaled and travel to the peritoneum through the lymph node system.
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As with other cancers, early detection of mesothelioma is important. Symptoms associated with peritoneal mesothelioma may mimic other, less serious problems, which makes diagnosing the disease even more difficult. If you have a history of asbestos exposure, you should ask your doctor about regular mesothelioma screenings.
Symptoms of peritoneal mesothelioma can include:
Because the above symptoms are not exclusive to peritoneal mesothelioma, the doctor will have to run several tests to reach a diagnosis. The initial step in diagnosing peritoneal mesothelioma involves a physical examination. The doctor will also take note of any history of asbestos exposure. If your physician does not inquire about your work history or exposure to asbestos, inform him of any risks you may have for developing mesothelioma. Failure to mention asbestos exposure can mean a delay in diagnosis and subsequent treatment.
After a physical exam, the doctor will order an imaging scan, such as an x-ray or MRI, of the abdomen. While these diagnostic imaging tools cannot confirm a diagnosis of peritoneal mesothelioma, they can indicate the presence of a tumor or abdominal fluid build-up. If excess peritoneal fluid in the found, a needle will extract a sample of the liquid to test for abnormal cells. Next, a biopsy will be performed to example the questionable tissues and cells in the abdomen. If a biopsy cannot be performed or results are inconclusive, a peritoneoscopy will be performed. During this test, a peritoneoscope will be inserted into the abdomen to collect a larger biopsy sample.
Since diagnosing peritoneal mesothelioma can be difficult, you should be honest with your doctor about any history of asbestos exposure. Even if you did not work with the material, a family member may have brought asbestos fibers home on their hair, skin or clothing. Early detection is vital in peritoneal mesothelioma patients, so sharing this information early can improve your prognosis significantly.