Nephrogenic Systemic Fibrosis and MRI Contrast Dye

When a doctor orders an MRI, the doctor may ask for contrast dye, which is a metallic ion called gadolinium. Gadolinium is a toxic substance that is usually safe because the manufacturers of MRI contrast dye encase it in a protective covering that prevents it from coming in contact with the interior of the body. However, patients with preexisting kidney problems may be unable to excrete the gadolinium from their bodies. Eventually the protective covering of the gadolinium breaks down and it comes into contact with the interior of the body which can cause a debilitating illness called Nephrogenic Systemic Fibrosis, NSF. NSF usually first manifests itself as a serious skin disorder and can be diagnosed by a dermatologist using a punch biopsy. Gadolinium is the only cause of this serious illness.